Friday, June 26, 2020

Live Attenuated Vaccines Could Protect against Most Severe COVID-19 Symptoms

Dr. Paul Fidel, Jr., from Louisiana State University Health – School of Dentistry and Professor Mairi Noverr from Tulane University School of Medicine propose the concept that administration of an unrelated live attenuated vaccine, such as the MMR (measles, mumps, rubella) vaccine, could serve as a preventive measure against the worst sequelae of COVID-19.

COVID-19 has not had a big impact on children, and the authors hypothesize that one reason children are protected against viral infections that induce sepsis is their more recent and more frequent exposures to live attenuated vaccines that can also induce the trained suppressive MDSCs that limit inflammation and sepsis.

Sci News

Live Attenuated Vaccines Could Protect against Most Severe COVID-19 Symptoms

29 comments:

hoonose said...

As a now retired doc I tried bringing this up on various medical and more political forums about a month ago, and met close to zero interest. I actually joined a study and donated a blood sample to measure my MMR AB levels. I recovered from a covid 19 infection this March, and had a positive covid 19 IgG AB test in May. The key here is that the MMR can be given to almost anyone starting right now. It has a very safe long term profile.

Peter Pan said...

Be a kid again. Go and play in the dirt.

Tom Hickey said...

@hoonose

Have you seen this?

There may be no immunity against Covid-19, new Wuhan study suggests

hoonose said...

Could be that many of those with low exposure and/or asymptomatic infection won't generate a good AB response. My wife and I are both AB positive now. She is immune compromised, and her bone marrow still hasn't fully recovered since our March infections. IMO we will see immunity of some duration in most recovered, and most likely with vaccines in a rough year time frame.

Matt Franko said...

hoo, Quest is saying the tests can only detect COVID not COVID 19

Probably all these new people have a common cold virus...

Matt Franko said...

btw Fauci has a BA in something called “classics” undergrad from Holy Cross..


Matt Franko said...

Here:

“Note: This test can sometimes detect antibodies from other coronaviruses, which can cause a false positive result if you have been previously diagnosed with or exposed to other types of coronaviruses.”

https://questdirect.questdiagnostics.com/products/covid-19-immune-response/b580e541-78a5-48a6-b17b-7bad949dcb57?utm_source=google&utm_medium=cpc&utm_campaign=71700000066217187&utm_content=58700005845625571&utm_term=p53388864417&gclid=EAIaIQobChMI2bHaid2g6gIVConICh22aAKXEAAYASAAEgJGbPD_BwE&gclsrc=aw.ds

Matt Franko said...

Common cold is a corona virus...

These Art Degree morons have destroyed the us economy for a common cold...

Greg said...

Common cold is just a corona virus, corona virus isn’t just the common cold

Very basic science error there Frankie boy

Peter Pan said...

An uncommon cold that spares kids and shoves boomers into their graves.

Show some gratitude for mother nature's efforts.

Matt Franko said...

Here’s another one:

Lede: “Coronavirus traces found in March 2019 sewage sample, Spanish study shows

https://www.reuters.com/article/us-health-coronavirus-spain-science-idUSKBN23X2HQ

Then it says: “There was the potential for a false positive due to the virus' similarities with other respiratory infections.“

Matt Franko said...

Many people who test positive never get sick...

So it’s obviously not what the test is detecting that is the real problem... yet they keep testing...

Fauci not qualified... and 79 years old and won’t retire should have been retired 20 years ago... old uneducated fart standing in the way of progress

Let someone qualified with a Science Degree run it we’d probably have many cures by now..

Matt Franko said...

Heres Fauci CV:

https://en.wikipedia.org/wiki/Anthony_Fauci

“Fauci attended Regis High School in Manhattan's Upper East Side, where he captained the school's basketball team and graduated in 1958.[9][5] He then went to the College of the Holy Cross, graduating in 1962 with a Bachelor of Arts degree in classics“

Unqualified...

AND HE WONT RETIRE!

This is like getting fossil clarinet player Greenspan to run the Central Bank...

Matt Franko said...

Here’s another one:

https://nypost.com/2020/06/25/getting-realistic-about-the-coronavirus-death-rate/?utm_medium=SocialFlow&utm_source=NYPOpinionTwitter&utm_campaign=SocialFlow

“ Unlike some other countries, the United States still hasn’t completed a national random antibody study — yet another way in which our public-health establishment has failed to get the data we need to make good decisions about lockdowns. But some counties, states and countries have.

SEE ALSO

Coronavirus cases in US could be 10 times higher than estimates: CDC
Those studies consistently show that far more people have been infected with and recovered from the coronavirus than suggested by data from tests that only measure current infections. Tests of municipal sewage systems — measuring the virus’ genetic signature in wastewater — have had similar findings.

Nearly all the studies find between 10 and 100 times the number of total infections as reported infections, with the average somewhere around 20 to 25 times.

In other words, while the CDC reports 2.34 million Americans have been infected with the coronavirus, the actual number of infected and recovered people may be closer to 50 million. (CDC Director Robert Redfield told journalists Thursday that the number of cases may be 10 times higher than the earlier 2.34 million.)

Thus, the death rate, which would be 5.2 percent based on that 2.34 million figure, is actually more like one-20th as high — or 0.26 percent.

To be sure, these estimates still have some uncertainty. The ­actual figure could be as low as 0.1 percent or as high as 0.4 to 0.5 percent, though treatment advances should mean it will trend lower over time. Even at 0.26 percent, the rate is still significantly higher than influenza most years, more comparable to a bad flu strain like the 1968 Hong Kong flu.”

Matt Franko said...

But if you talk to the test people they come right out and tell you their antibody test just detects ANY corona virus antibody...

So if you had a cold ever in your life they say you had COVID-19....

We need to clean house of ALL Art Degree people...

hoonose said...

As we have progressed through the virus timeline the accuracy and specificity of the testing has improved. Of course there are still some false pos and neg, but improving over time.

Mass testing on large groups is mainly an epidemiological study. What is more important is hospitalizable cases. And colds don't do that. Really sick patients in the hospital mostly test pos. And most testing out in the public is neg, so far. And the vast majority of the public has had a cold now and again.

Fauci has been our infectious disease and pandemic leader for decades, going back to the '80's with AIDS. He has been fully and then constantly vetted all along by experts all over the world since then and remains our fearless leader here today. Back in the '60's and '70's, med school acceptance committees began a quest for diversity. So applicants back then in totally unrelated fields were given some preference for admission. Like song and dance. My own key in was through gymnastics. The specifics of undergrad work has little impact on how good a doc you will turn out to be.

Matt Franko said...

Well at least you got body mechanics thru the athletics...

And had to learn how to make proper corrective adjustments thru repetitive training...

Fauci trialed how to ignore evidence and maintain opposing dialog.. not an applicable skill here...

S400 said...

Haven’t the wind of god taken care of covid-19 yet?
It’s months since that pastor blew into the camera.

Calgacus said...

Matt, you've got to be kidding. Fauci then graduated first in his med school class from Cornell.
Or is anyone who has ever taken a non-science course, even in grade school, "unqualified"?

Met an old school friend of my mom's - who happened to have given Fauci a job out of med school, still sees him occasionally and thinks the world of him.

Again, those qualified to give an informed opinion know that ignoring evidence and the opponents position in a dialog is the opposite of what "humanist" "art degree" education is supposed to provide. While people in and out of the sciences may not behave according to these "shoulds" - nobody whatsoever says that ignoring evidence and arguments is the right way to behave in any discipline.

S400 said...

Classic Matt Franko; cherry pick in absurdity.

Peter Pan said...

For cherry picking, bring your own baskets - Farmer Pan.

Protests, riots and feelings of righteousness builds up viral immunity - US Health experts.

Matt Franko said...

“ Fauci then graduated first in his med school class from Cornell. ”

I know and that is SCARY!!!!

Matt Franko said...

Here:

https://plato.stanford.edu/entries/hegel-dialectics/

This what you people are doing...

Do a control-F on “evidence” or “test” here... or “empirical”.... they DONT appear...

HERE:

“ Hegel’s dialectics” refers to the particular dialectical method of argument employed by the 19th Century German philosopher, G.W.F. Hegel (see entry on Hegel), which, like other “dialectical” methods, relies on a contradictory process between opposing sides.

It doesn’t rely on evidence or testing..., it simply relies on the methodology of the dialog itself...

We trained in the Science side of the academe DO NOT DO THIS... we are trained to proceed with purpose and creativity and to immediately yield to the true and reject the false...

This is NOT how you people are trained.... you are trained to reason/dialog... you are trained to NOT be subject to truth...





Matt Franko said...

Fauci big Hillary lover:

https://twitter.com/thelastrefuge2/status/1277092949386461184?s=21


He is not a scientist... he’s a Platonist trained politician...

Should have handed it over to a better trained GenXer 20 years ago...

S400 said...

“we are trained to proceed with purpose and creativity“

You failed in creativity. So your not trained. Too bad.

Matt Franko said...

I create things all the time...

Matt Franko said...

Things that actually work... and if they don’t work, I throw them out and start all over again...

You disgraced pieces of human garbage just double down on your stupid...

Calgacus said...

(1/2)

Matt, not to be hostile, but you are talking about things which you don't really understand. And which you have gotten extremely strange ideas about, which in many respects are the exact opposite of what is universally understood.

I am a science guy, even more a math guy. The reason/dialog/dialectic stuff is just "the scientific method" by another name. It's all about rejecting the untrue, aiming at the true.

That's what "dialectic" means - philosophical debate aimed at truth. Period. Where "philosophy/philosophical" means trying to consciously understand what you are saying, each word, each step, no handwaving, no magical shortcuts. And nothing else. My definition here is better than some longwinded blah-blah from some encyclopedia, which I recommend forgetting.

Opposing dialectic etc is saying I don't care about truth, I don't care about understanding.

we are trained to proceed with purpose and creativity and to immediately yield to the true and reject the false...

That's not being a scientist, that is being God. Science, for humans, is hard.

It doesn’t rely on evidence or testing..., it simply relies on the methodology of the dialog itself...

Yes, because what the dialectic is being applied to is things - concepts, theories, that have already been "derived" from evidence, testing, empirical sciences, from looking out the window. But the usual state of affairs then is a bunch of mutually contradictory theories. You whack them against each other, and try to get something better, of which each theory, concept whatever you started with is a specialization, a facet of.

Calgacus said...

(2/2)

Hegel said a few dumb things - who hasn't? But he is enormously slandered, even still. Look at the beginning of his Philosophy of Mind/Spirit (his Encyclopedia vol III), where he emphasizes the dependence of Philosophy on the empirical/natural sciences, which are what Philosophy munches on - and which is why good scientists are the truest fans ( or creators) or genuine philosophy, because it helps them understand themselves and their own work.

A good rule is that the more a philosopher or thinker has the rep of being a priori theory-spinner out of his butt, and not looking at experiment etc, the more he does. And the ones who pose as listening to science and following some scientific method, the more likely it is just vacuous and ignorant of both science and philosophy.

Maxwell's electromagnetism is a classical example. Experiments and theories from electricity, from magnetism, from optics (and Newtonian or fluid mechanics) gave theories that it took a great genius to put together (relying on the work of an only slightly lesser genius, Faraday, who was not enough of a mathematician to understand that he Faraday himself was a major mathematician. Maxwell was, uniquely able to see Faraday's math - and to "dialectically" synthesized a new theory. And the dialectic was further applied by Einstein to see that Special Relativity really was "already in" Maxwell's theory. You just gotta try to eliminate the internal contradictions.


We trained in the Science side of the academe DO NOT DO THIS.
Very wrong. Tragically wrong. The only accurate thing is that we often don't do this - and that is a terrible thing. People pretend they understand things when they don't. For emotional, egoistic reasons they avoid talking to other (feuding) scientific sects, even when all know that they should. When we DO NOT DO THIS, Science suffers. When we DO THIS - it progresses far faster.

The dialectical/ philosophical part comes very easily to the real math/science guy. Because then they have the experience of having sat in ( or taught :-) ) numberless classes or seminars, where you know what is being said is true, it might even be earthshaking - but on some level, you know you simply don't understand it, even if it is coming out of your own mouth! And the lecturer may only have a dim grasp too. Which is why real science guys welcome genuine "dialectic", if they can stop being autistic for a while,

You can go a long way in science or math in the cartoon character way of walking on thin air. But the dialectical/philosophical part is when you look down. The goal is the magical revivification of the character after he falls.